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The 2016 meta-analysis (Pooyandjoo, PMID 27335245) pooled trials of varying length and found a mean 1.33 kg difference versus control, but its meta-regression reported that the weight advantage shrank as supplementation continued so the weight effect does not compound across this window the way recovery adaptations do

More specifically, the researchers share that they conducted an additional investigation into the potential of CJC-1295 on a murine model of GHRH gene ablation (GHRHKO) and related growth decline

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